Coach Avram Grant has handed striker Kwesi Appiah and Ibrahim Moro starting roles in the pre-AFCON friendly against Olhanense today.
The duo are amongst three uncapped players who have been included in the 26-man provisional squad for the tournament.
Ernest Sowah starts in post while Samuel Inkoom, John Boye, Awal Mohammed and Edwin Gyimah form the defensive unit for the Black Stars in the game which will be played on Wednesday afternoon at the Algave stadium in Portugal.
The central midfield trio includes Ibrahim Moro, Afriyie Acquah and Frank Acheampong.
In attack, Kwesi Appiah will lead the triangle which will have Christian Atsu and Mubarak Wakaso on the flanks.
Black Stars starting lineup for Olhanense friendly:
Ernest Sowah, Samuel Inkoom, John Boye, Awal Mohammed, Edwin Gyimah, Afriyie Acquah, Frank Acheampong, Ibrahim Moro, Mubarak Wakaso, Christian Atsu, Kwesi Appiah