The Black Meteors will face Dreams FC in a friendly at the Accra Sports stadium at 3pm on Wednesday.
The team has been camping at the Ghanaman Centre of Excellence at Prampram and will use the test match to assess their readiness for the 2023 U-23 Africa Cup of Nations qualifiers against Mozambique.
Ghana drew a bye in the first of a three-round qualifying series for the tournament to be staged in Morocco next year.
Mozambique defeated Mauritius 5-1 on aggregate in the first round to set up the Ghana tie.
Coach Ibrahim Tanko and his charges are expected to travel to the East African nation for the first leg before hosting their opponents in the 2nd leg at the Cape Coast Sports Stadium.
The first and second legs are scheduled for October 21-23 and October 28-30 respectively.