Asante Kotoko, Medeama and Berekum Chelsea seek to add the another domestic Cup to their list of possible titles this season when they take their turn in the MTN FA Cup on Sunday.
The premiership trio, who are all involved in CAF Club competitions will get the third-round FA Cup campaign off before turning their sights to their continental fixtures next week.
Cup holders, Medeama will welcome Pure Joy to the T&A Park where they hope their defence of the title will not be scuppered by the second-tier side.
At the Baba Yara Stadium, Kotoko are aware an upset could happen when they take on third-tier side First Klass.
The fixture dates and venues for the third-round stage of the MTN FA Cup has been decided with the last of 32 action starting on February 2.
Berekum Chelsea will play away to UCC Youngsters at the Robert Mensah Stadium.
Round of 32 Pairings
Sunday, February 2
Medeama vs Pure Joy - T&A
First Klass vs Asante Kotoko - Baba Yara
UCC Youngsters vs Berekum Chelsea - Robert Mensah